1. Quercetin Overview
Where to buy Quercetin Powder with lowering Quercetin price and high quality? Where to find good information of Wholesale Quercetin and Purchase Quercetin for sales? As the professional Quercetin manufacturer, Plamed is your best choice.
Quercetin, also known as 5-hydroxyflavone, is a kind of polyhydroxy flavonoid. Quercetin is widely found in various vegetables, fruits and botanical drugs in nature. For example, it is abundant in sophorae, onion, honey and wine. And it is easy to extract, separate and detect. Plamed Quercetin is extracted from dried flower bud of Flos Sophorae, and is natural cosmetic ingredient with purity up to 98%. Quercetin is yellow crystalline powder. It is almost insoluble in cold water, slightly soluble in boiling water. Quercetin is soluble in boiling ethanol and sodium hydroxide solution.
In recent years, Quercetin has been increasingly popular in cosmetics industry. Quercetin can absorb ultraviolet rays strongly. It can be used in sunscreen cosmetics. Its combination with kojic acid can enhance both stability of kojic acid and whitening property of cosmetics. Quercetin can be used with metal ions as hair dyes. Quercetin can also acts as an anti-inflammatory agent to soothe skin and reduce facial redness. Meanwhile because of its anti-inflammation and free radical scavenging ability, Quercetin can prevent fine lines and wrinkles. It is good anti-ager, antioxidant and skin tightening agent. In addition, Quercetin is thought to be pilatory and relieve oily skin.
|Product Name||CAS Number||INCI|
|Molecular Weight||Molecular Formula||Molecular Structure|
|Product ID||Specification||Minimal Package||Minimal Order Quality|
2. Quercetin Source
Sophora japonica is a plant of genus Sophora in Leguminosae family. It is a kind of perennial deciduous tree. It is a great species for timber-used, medicine, food and appreciation. Sophora japonica’ s flower is called Flos Sophorae; its flower bud is known as Flos Sophora immaturus, and it is ovate or ellipsoidal. Sophora japonica is native to China. There are wild and cultivated Sophora japonica in north and south parts of China. It is particularly common in Loess Plateau and North China Plain. It is mostly found on plain, near villages, mountains and foothills. It is also cultivated in Vietnam, Korea, Japan and Europe. Flos Sophorae is rich in rutin and flavonoids; and it also contains beta sitosterone, tannins, amino acids, proteins, vigabatrin and trace elements. Flos Sophorae immaturus is a traditional Chinese medicine ingredient. It is widely used in medicine and health care products.
3. Quercetin Manufacturer Specifications
|Color||Yellow crystalline powder|
|Particle size||98% through 80 mesh|
|Total Plate count||≤1000cfu/g|
|Yeast & mold||≤100cfu/g|
4. Quercetin Manufacturer Flow Chart
5. Quercetin Benefits
Quercetin is a superoxide anion scavenger. Its mechanism of anti-free radical and inhibiting lipid oxidation is as follows: It binds iron ions to form inactive complexes; and then it prevents iron ions from participating in biochemical reactions that can produce many free radicals. In the meantime, Quercetin can maintain activity of free radical scavenger of the complexes. There are three main ways that Quercetin prevents free radicals formation: (1) It has complexation capability with superoxide anions to reduce production of oxygen free radicals. (2) It binds iron ions to prevent formation of hydroxyl radicals. (3) Quercetin inhibits aldose reductase, and reduces reduced coenzyme Ⅱ (NADPH) consumption. Thereby, Quercetin improves its anti-oxidation property.
- Anti-bacterial and antivirus
Quercetin can inhibit uncoating of lysosome H+-, ATP enzyme and phosphatase A2. It affects phosphorylation of virus transfer genes. Also, Quercetin inhibits viral protease and RNA synthesis. Therefore, Quercetin has anti-bacterial and anti-viral effect.
- Anti inflammation and anti allergic
Quercetin can inhibit cell lipooxidase and epoxidase, which can restrain synthesis of leukotrienc and prostaglandin. Thus, it acts as an anti-inflammatory and anti-allergic agent.
- Sun protection
The characteristic peaks of ultraviolet absorption of Quercetin are 350nm and 258nm. Quercetin has strong ultraviolet absorption capacity as well as anti-phototoxic effect. It can alleviate sunburn and discoloration caused by sun exposure. Quercetin can be used as sunscreen in cosmetics.
6. Study on the Pharmacology of Quercetin and Cosmetics
|Elimination to DPPH free radicals||EC50: (14.91±2.74) μg/mL|
|Elimination to singlet oxygen radicals||0.03%||Elimination rate: 72%|
|Inhibition to xanthine oxidase activity||IC50: (5.6±0.4) μg/mL|
|Inhibition to lipid peroxidation||6.7μg/mL||Inhibition rate: 89.6%|
|Promotion to hyaluronic acid production by cell culture||1μmol/L||Promotion rate: 110.3 (blank 100)|
|Inhibition to phototoxicity||IC50: 0.005%|
|Inhibition to the activity of 5α-enzymes||0.5μg/mL||Inhibition rate: 34.3%|
|Inhibition to sebum secretion when applying on skin||2%||Inhibition rate: 13.0%|
|Contraction to pore diameter when applying on skin||2%||Contraction rate: 26.1% (compare to blank)|
|Inhibition to MMP-1 activity||10×10-6||Inhibition rate: 35%|
|Inhibition to MMP-3 activity||20μmol/L||Inhibition rate: 33.4%|
|Inhibition to IL-4 production||200μmol/L||Inhibition rate: 16.6%|
|Inhibition to ear swelling induced by xylene in mice||0.5mg/ear||Inhibition rate: 55.9%|
7. Plamed Quercetin Characteristic
- The raw material of Quercetin adopts high quality flos sophorae;
- Plamed Quercetin is of stable quality.
8. Quercetin Application & Dosage
Quercetin is mainly applied in sun protection cosmetics. It can also be used as an antioxidant and anti-inflammatory agent in various skin care products including face cream, lotion, essence and toner. Meanwhile, because of its yellow powder appearance, Quercetin can be used as a natural hair dye.
- Quercetin is photosensitive; its color will change from yellow to yellowish green when exposing to light. So it must be away from light and stored under low temperature.
Quercetin application cases in major cosmetic brands in the world:
|USA||Paula’s Choice||RESIST Super-Light Daily Defense SPF 30
Resist ultra-light Super Antioxidant Concentrate Serum
Resist Advanced Replenishing Toner
|Elta MD||UV Physical Broad-Spectrum SPF 41
UV Lip Balm Broad-Spectrum SPF31
|Dr. Dennis Gross||Ferulic Acid + Retinol Brightening Solution
Ferulic + Retinol Triple Correction Eye Serum
Smooth and Radiant Kit with Brightening Solution
|ARCONA||Magic Green Ice|
|Epionce||Renewal Facial Lotion
Anti-Aging Lip Renewal 0.42 oz
|Switzerland||La Prairie||Cellular Swiss Ice Crystal Cream
Cellular Swiss Ice Crystal Dry Oil
Cellular Swiss Ice Crystal Emulsion
Cellular Swiss Ice Crystal Eye Cream
|Spain||Sesderma||FACTOR G RENEW Reiuvenating serum|
|China||RUNA||Noni Leaf Intensive Repairing Milk Bio-Cellulose Mask|
|Alleluia||Soften Repair Cream|
|UZERO||Black Rose Moisturizing Facial Mask
Black Bean Moisturizing Mask
|Australia||Canvas||Firming Night Care
Brightening Day Care
Protective Day Care
Illuminating Beauty Balm
|Italy||Borghese||DN Active Future Youth Resculpt Body Lift|
|Korea||Dr. Time Peel||Acne Repair Essence|
9. Quercetin Reference Formula
|Vitamin B6||0.05||Fragrance, preservative||Appropriate|
Whitening skin care cream
|A phase||Quercetin||0.39||Ferulic acid||0.25|
|Piperine||0.36||Absolute ethyl alcohol||10.0|
|B phase||Isopropyl isostearate||1.5||Isooctyl palmitate||4.0|
|Squalane||2.0||C12-15 alkyl benzoate||2.0|
|Stearic acid||1.0||Caprylic acid/triglycerides||6.0|
|C phase||Hyaluronic acid||0.05|
|D phase||Glycerin||3.0||Propylene glycol||2.0|
|Methylparaben||0.2||0.5% konjac glucomannan KJ-30||50.0|
|Water||Add to 100|
10. Quercetin Safety
- Quercetin has been considered as cosmetic raw material by Cosmetic, Toiletry & Fragrance Association (CTFA).
- Quercetin is listed on The International Catalogue of Chinese Cosmetic Raw Materials Standards in 2010 published by CAFFCI, and On the Announcement of Name List of Cosmetics Raw Material issued by CFDA in 2014.
11. Packing and Storage
Package: Packed in 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
Plamed Mission: To be the most professional supplier of natural cosmetics raw material.
As a professional Quercetin manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good Quercetin and good Quercetin price will help customers make good terminal products and help customers win a lasting and broad market.